Division Leader: Franco Calabi
General Research Interests
- Novel materials and micro/nano devices and technologies for analytical/diagnostic applications in the Life Sciences and particularly in Medicine
- Tissue Engineering
Technologies
- Cell and Molecular Biology: Recombinant DNA technologies, Protein design and expression; Stem Cells
- Chemistry: Nanoparticle synthesis and functionalisation; Surface patterning and functionalisation
- Characterization: Optical microscopy (wide-field (including time-lapse) and confocal (1- e 2- photon, spectral analysis)), electrochemistry, dynamic light scattering
Current Projects
- Optical nanobiosensors for functional analysis (eg activation state of transcription factors) in living cells
- Microfluidic reactors for the clonal analysis of stem cells
- Stem cell microarrays
- Bioreceptor microfluidic chips for HTS of ligands and/or combinatorial analysis of complex mixtures of analytes
- Design of allosteric bioreceptors for the label-free detection of proteins and their post-transalational modifications
Funding
- MIUR Grant RBLA03ER38: National Laboratory for Nanotechnology applied to Genomics and Post-Genomics
- MIUR Grant RBIN04H5AS: From molecules to behaviour: understanding the neurobiological basis of plasticity and learning
- IIT Project “Cells to chips and chips to cells”
External collaborations
- Prof. Emilio Bizzi, Dept. Brain and Cognitive Sciences, Massachusetts Institute of Technology, Boston, USA
- Prof. Antonino Cattaneo, European Brain Research Institute, Roma, Italy
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